Sarcomas are rare cancers, accounting for <1% of all malignancies. They originate in either bone or soft tissue.
Several types of benign or non-cancerous bone tumors can become cancerous. The most common cancerous bone tumors are plasma cell tumors that arise from bone marrow, and osteosarcomas, chondrosarcomas and Ewing’s sarcomas, which are from the bone itself. Bone sarcomas are rarer than soft tissue sarcomas, with about 3,000 new cases in the United States each year.